Diabetes mellitus in newborns is extremely rare.
He might be:
1. PRIMARY, genetically determined, with polygenic
type of inheritance. A genetic defect is realized either in the form of
prolongation of the synthesis, release, neutralization or destruction of insulin,
Bo by increasing insulin resistance of insulin-dependent tissues.
2. SECONDARY, with infectious and dystrophic lesions of the islet
apparatus for cytomegaly, toxoplasmosis, tuberculosis, syphilis, muco-
viscidosis, isoserological conflicts, in the presence of anti-insulin
antibodies.
Clinical symptoms appear in the first days or weeks of life.
Children are born on time, but with a weight of less than 2500 grams. Their skin
flabby, wrinkled. They are restless, do not withstand the timing of feeding.
Thirst, polyuria are expressed . Dehydration may develop. Often from
rushing hyperthermia. Persistent constipation. Progressive exhaustion.
May be congenital cataract and hydrocephalus. Early joining
pustular skin diseases, diaper rash, and possibly the development of septicemia
sis.
In the blood – hyperglycemia.
In the urine – glucosuria.
Diabetic coma in a newborn is usually taken for
manifestation of infection, as dehydration is observed, inadequate
breath.